Sure, visiting these cities in the UK can provide plentiful experiences encompassing history, culture, and entertainment. Here are some travel tips:

Best Time to Visit:
April to June is the best time when typically the weather is mild, and many outdoor attractions are open. September to November can also be good as the summer crowds would have gone but weather is unpredictable.

Route and Accessibility:
These cities are well connected by train services, and you can easily book your journey online without much hassle. Alternatively, buses are considerably cheaper but take longer. Domestic flights are also available.

Altitude and Acclimatization:
These cities are near sea level so no acclimatization is required.

Accommodation and Booking:
Choosing accommodation near city center or near public transportation hub will be beneficial. Booking in advance, especially during peak season and for popular locations, is recommended. Airbnb, Hotels.com, Booking.com are some of the platforms where you can book your stay.

Clothing and Essentials:
Pack layers as UK weather can be quite changeable. A waterproof layer is recommended due to frequent rain. Comfortable shoes for walking are also recommended as these cities are best explored on foot. Don't forget your adapters for electrical outlets.

Health and Safety:
UK is fairly safe, but usual precautions should be taken. Follow the local Covid-19 guidelines. If you're on any medication, bring adequate supplies as getting a prescription can be cumbersome.

Local Etiquette and Respect:
UK citizens are polite and queue-loving. Respecting the local traditions, especially in pubs and restaurants is important. Tipping is customary in the UK, usually around 10-15% of the bill.

Enjoy your trip to the UK - it's a country steeped in history but with a firm eye on the future. Safe travels!