Hello! It's exciting that you're planning a trip to Prague, Vienna, and Budapest. These are wonderful destinations full of rich history and stunning architecture. Here are some travel tips for you.

Best Time to Visit:
The best time to visit these Central European cities is in the spring (April-June) or fall (September-October), when the weather is pleasant and the tourist crowds are thinner than in the summer. The Christmas season is also special with beautiful markets, but it can be quite cold.

Route and Accessibility:
These cities are easily accessible by air, with international airports in all three locations. You can start your trip in any one of these cities based on your preference and flight availability. Moving between cities is convenient by train or bus. RailJet operates high-speed trains between these cities which are comfortable and efficient.

Accommodation and Booking:
You'll find a wide range of accommodations in Prague, Vienna, and Budapest, from prestigious hotels to budget-friendly hostels. Booking in advance is always recommended, especially during the peak tourist season.

Clothing and Essentials:
Pack according to the season of your visit. In spring and fall, layering clothes is a good idea due to the varying temperatures. Comfortable walking shoes are a must, as these cities are best explored on foot. An umbrella or raincoat might be handy. Don't forget your travel adapter for electronics, as Central Europe uses a two-pin plug (Type F).

Health and Safety:
These cities are generally safe but common sense should always be exercised. Beware of pickpockets in crowded tourist areas. In terms of health, no special vaccinations are needed for travel in these cities. European Health Insurance Card (EHIC) holders can access health care during their visit.

Local Etiquette and Respect:
People in these cities appreciate good manners. Being polite, always saying please ('prosím' in Prague, 'bitte' in Vienna and 'kérem' in Budapest) and thank you ('děkuji', 'danke', 'köszönöm' respectively) is appreciated. It's also beneficial to follow local customs and rules, such as not jaywalking in Vienna as it's frowned upon.