Hello! It's great to hear that you're planning a trip to the beautiful cities of Madrid, Barcelona, and Valencia in Spain. I'm sure you'll have an amazing time exploring the rich culture and stunning architecture.

Best Time to Visit:
The best time to visit Madrid, Barcelona, and Valencia is during the spring (March to May) and autumn (September to November). The weather is mild and pleasant during these times and you can avoid the summer crowds.

Route and Accessibility:
All three cities have international airports and are well-connected by Spain's high-speed train network, the Renfe. You can fly into Madrid and take the train to Barcelona and Valencia. Buses and taxis are readily available in all three cities for local transportation.

Accommodation and Booking:
All three cities have a wide range of accommodations to suit every budget. It's recommended to book in advance, especially during the peak seasons of spring and autumn, to secure your preferred accommodation. Online booking platforms can provide multiple options and reviews to help you choose.

Clothing and Essentials:
Packing for Spain's Mediterranean climate means light clothing for the warm days, a sweater or jacket for cooler evenings, comfortable walking shoes for sightseeing, sunscreen, and a hat for sun protection. Don't forget your beach attire if you plan to visit Valencia's beautiful beaches!

Health and Safety:
Spain is generally safe for tourists, but just like anywhere, be cautious of your surroundings, particularly in crowded tourist areas where pickpockets may be operating. Basic health facilities are available widely. It’s advisable to get an EHIC (European Health Insurance Card) or good travel insurance.

Local Etiquette and Respect:
Spanish people are generally warm and friendly. They appreciate it when visitors try a few phrases in Spanish. Remember to respect local traditions and customs. In most places, it is customary to tip 10% of the bill.