Absolutely! A trip to Mexico City, Cancún, and Guadalajara has a lot to offer - from vibrant city life to mesmerizing beach views. Here are some travel tips to help you with your trip:

Best Time to Visit:
The best time to visit Mexico City and Guadalajara is between March and May, while for Cancun it's from December to April. These periods offer pleasant weather ideal for sightseeing and beach activities.

Route and Accessibility:
Direct international flights are available to all three cities. For internal travel, you can consider domestic flights, buses or rent a car depending upon your convenience and budget.

Altitude and Acclimatization:
While Mexico City is located at a high altitude, both Cancun and Guadalajara are near sea level. Take a day or two to adjust to the altitude when arriving in Mexico City to avoid altitude sickness.

Accommodation and Booking:
All three cities offer a range of accommodations to suit different budgets. It’s wise to book your accommodations and any specific activities or tours in advance, especially during peak seasons.

Clothing and Essentials:
Pack lightweight clothing for Cancun's tropical climate, and warmer clothing for Mexico City. A good quality sunscreen, hat and some beachwear are must-haves for Cancun. Don't forget comfortable walking shoes for sightseeing tours in all three cities.

Health and Safety:
Make sure to have travel insurance that includes medical cover. Stay hydrated, especially in Cancun's humid climate. Be cautious while using public transport and avoid isolated areas at night.

Local Etiquette and Respect:
Mexicans are known for their friendliness and warmth. Greetings are important, and a simple "Hola" can go a long way. In Mexico City and Guadalajara, tipping is a common practice in restaurants, bars, and for service providers. In Cancun, dress modestly when not on the beach.

Remember to respect local traditions and culture, enjoy the delicious cuisine and have a great trip!