Hello! It's great to hear you're planning a trip to Egypt, particularly to Cairo, Luxor, and Aswan. Below are some insights that might be helpful to you.

Best Time to Visit:
The best time to visit these cities is during Egypt's cooler months, from October to April as summers can be extremely hot. For sight-seeing, the periods from December to January and Easter are popular among tourists, albeit busy.

Route and Accessibility:
Cairo has an international airport that connects to several global destinations. From Cairo, one can take a train or domestic flight to Luxor and Aswan. Egypt has a well-connected public transport network, and hiring a taxi or car is also convenient.

Accommodation and Booking:
All three cities offer a wide range of accommodations, from luxury hotels to budget-friendly guest houses. It's best to book your accommodations in advance especially during peak season. Online platforms like Booking.com or Airbnb offer numerous options.

Clothing and Essentials:
Light, cotton clothing is recommended given the hot climate. Don't forget a good sun hat, sunscreen, and sunglasses. Carry a water bottle to stay hydrated. Modest clothing is advised while visiting religious sites.

Health and Safety:
Choose bottled water over tap water to avoid any potential health issues. Basic healthcare facilities are available in these cities, but it's recommended to have travel insurance. Be aware of your surroundings and take care of your belongings as tourist spots can be crowded.

Local Etiquette and Respect:
Egyptians appreciate polite behavior. Dress modestly, especially when visiting religious sites. Tipping is common in Egypt so keep some change handy. Always ask for permission before photographing locals.