Absolutely, I'd love to help plan your trip to Barinas, Maracay, and Coro in Venezuela. Here's what you need to know:

Best Time to Visit:
The best time to visit these places is during the dry season i.e., from October to April, when the weather is more stable. Avoid the rainy season (May to September) due to possible heavy rains.

Route and Accessibility:
A car or bus is the best way to travel between these cities. Barinas to Maracay can be covered by road which takes about 6 hours. While, Maracay to Coro is again a 5 hours journey by road.

Altitude and Acclimatization:
These locations are not located at high altitudes therefore, acclimatization is not a concern.

Accommodation and Booking:
There is a wide range of accommodation options from budget hostels to luxury hotels in all these cities. It's advisable to book your accommodation in advance especially during peak season.

Clothing and Essentials:
Pack light clothing as temperatures are generally warm. However, do carry a raincoat or umbrella if you are visiting in the rainy season. Also, don't forget to pack sun protection like a hat, sunglasses, and sunscreen.

Health and Safety:
Always use bottled water for drinking. Try to eat at hygienic places. It's highly advisable to have travel insurance to cover any unexpected incidents or health issues. Always carry an ID, and be careful with your personal belongings.

Local Etiquette and Respect:
Venezuelans are known for their friendliness and hospitality. Try to learn a few basic Spanish phrases as it's their official language. Always respect the local customs and traditions. When visiting religious sites, dress modestly.