Absolutely! Here are some tips for your travels to Brighton, Portsmouth, Bournemouth, and Exeter in the UK:

Best Time to Visit:
The most suitable time to visit these British cities is during the summer months (June to August) when the weather is pleasant and outdoor activities are predominant3. However, if you wish to avoid crowds, consider going in the spring (April to June) or autumn (September to November).

Route and Accessibility:
Start from London, which is a hub for all such cities. You can easily reach these cities through train or coach. National Rail services operate between these cities regularly4.

Altitude and Acclimatization:
Situated at sea level, you need not worry about altitude acclimatization for these cities.

Accommodation and Booking:
Each of these cities offers a wide array of accommodations, from budget hostels to luxury hotels. It's advisable to make bookings in advance to avoid last-minute inconveniences, especially during the peak seasons.

Clothing and Essentials:
Packing for your trip largely depends on the season. For summer, bring light clothing, hats, sunglasses, and sunscreen. For cooler months, pack warm clothing like jacket, scarf and gloves.
Don't forget to pack a waterproof jacket or umbrella, as the UK is well-known for its unpredictable rain showers.

Health and Safety:
All these cities are reasonably safe, but as with any other travel destination, exercise common sense such as not walking alone at night in less crowded places, keeping your belongings secure, etc.

Local Etiquette and Respect:
British people value punctuality, politeness, and good manners. Observe local customs, be patient, and respect queueing etiquette.

Please be aware of COVID-19 protocols - maintain social distancing and follow local government guidelines.

Enjoy your trip!