Absolutely, Portugal's Algarve region overflows with picturesque landscapes such as Faro, Albufeira, Lagos and Sagres. Here are some tips to help you enjoy your travel to the fullest.

Best Time to Visit:
The best time to visit these places is from March to June and from September to October, when the weather is mild and there aren't too many tourists. Avoid July and August as it can get crowded.

Route and Accessibility:
The Algarve is well connected with the rest of Portugal. Faro is the primary airport in the region. You can rent a car to travel to Albufeira, Lagos, and Sagres, or use public transport. Trains and buses operate regularly.

Altitude and Acclimatization:
These locations are at sea level and hence there is no need to worry about altitude sickness or acclimatization.

Accommodation and Booking:
Ensure to book your accommodation in advance, especially if travelling during peak season. There are options catering to different budgets, from luxury hotels to cozy guesthouses.

Clothing and Essentials:
Pack both light and warm clothing to adapt to the changing temperatures. Also remember to carry a good sunblock, swimwear, beach towel, comfortable footwear and a hat.

Health and Safety:
Keep yourself hydrated. If you're planning on participating in water sports, ensure you follow all safety instructions and regulations.

Local Etiquette and Respect:
It's best to respect local traditions. Portuguese people appreciate courtesy, and attempt to speak a few local phrases would be appreciated. Do follow dress regulations if visiting any religious sites.