Hello! It's great to hear that you're planning a trip to the scenic cities of Nantes, Angers, Le Mans, and Tours in France. Here are some travel tips for your journey.

Best Time to Visit:
The best time to visit these cities is from May to September when the weather is warm and pleasant. However, these cities are beautiful throughout the year and each season brings its own charm.

Route and Accessibility:
All of these cities are well connected with each other and can be reached via train, bus, or car from major cities of France. Regular flights are also available to Nantes', Angers', Le Mans' and Tours' airports from various French cities and international destinations.

Accommodation and Booking:
Each city offers a range of accommodations, from budget hostels to luxury hotels. It's best to book your stay well in advance, especially during the peak tourist season (May-September). You can use online booking platforms like Booking.com, Airbnb, and others for reservation.

Clothing and Essentials:
Pack light, breathable clothing for the summer months, along with a good-quality sunscreen. For autumn and winter travels, warm clothing is a must. Also, don't forget to carry a good pair of walking shoes as these cities are best explored on foot.

Health and Safety:
France has a high-standard healthcare system, but don't forget to have your travel insurance in place. Keep emergency numbers accessible and maintain basic precautions like keeping your belongings safe. It's also important to stay hydrated and protect yourself from the sun.

Local Etiquette and Respect:
French people greatly appreciate it when travelers make an effort to speak their language, even simple phrases. Remember to greet people with a simple 'Bonjour' (Hello) or 'Bonsoir' (Good evening). It's also customary to say 'Merci' (Thank you) and 'S'il vous plaît' (Please).