Absolutely! Traveling to these regions in Russia is quite an adventure. Here are some travel tips to assist:

Best Time to Visit:
The best time to visit these areas is during summer (June, July, and August). Winters could be very harsh, particularly in Yakutsk which is known as the coldest city in the world.

Route and Accessibility:
Vladivostok, Khabarovsk, and Blagoveshchensk are all easily accessible by train, as they are stops along the Trans-Siberian Railway. You can also get to these cities by plane. To reach Yakutsk, however, one would typically fly in via Moscow.

Altitude and Acclimatization:
There isn't much of a high altitude concern with these cities as they are all relatively low-lying. However, do remember to book a few days of rest to get acclimatized, especially if you're flying in directly.

Accommodation and Booking:
There are plenty of accommodation options in these cities, you can book hotels or guesthouses online in advance. Keep in mind, English might not be widely spoken so having a translation app might be helpful.

Clothing and Essentials:
In the summer, moderate clothing should suffice but always bring some layers as it can get chilly at night. However, if you’re planning to visit in winter, you must bring heavy, well-insulating clothing, gloves, scarves, and thermal boots.

Health and Safety:
Check with your healthcare provider regarding any specific vaccinations required for traveling to these regions in Russia. Also, have a well-prepared first-aid kit with you along with any prescribed medication.

Local Etiquette and Respect:
Russians are warm and hospitable, although they may appear reserved initially. Dress modestly when visiting religious sites and respect local traditions. Also, learning a few basic Russian phrases can go a long way and is much appreciated. Remember, it's customary to refuse a gift before accepting it.