Sure! Planning your visit to these dynamic Vietnamese cities is an exciting adventure. Here are some helpful travel tips:

Best Time to Visit:
The best time to visit Ho Chi Minh City, Cần Tho, and Vung Tàu is during the dry season from December to April. During this time, the weather is sunny and less humid, making it ideal for exploring the cities.

Route and Accessibility:
Ho Chi Minh City is well-connected with international and domestic flights. From there, you can take a domestic flight or a bus to reach Cần Tho. For Vung Tàu, the most convenient method is to take a two-hour ferry ride from Ho Chi Minh City, or you could opt to travel by bus or car.

Altitude and Acclimatization:
Ho Chi Minh City, Cần Tho, and Vung Tàu are all at low altitudes, so acclimatization is generally not a problem.

Accommodation and Booking:
These cities offer a range of accommodations to fit every budget. It's advisable to book your accommodations in advance, especially during peak tourist season (December - February).

Clothing and Essentials:
Pack light, breezy clothing for the tropical climate. A light jacket or shawl might be needed for air-conditioned places or cooler nights. Don't forget your sunscreen, hat, and sunglasses.

Health and Safety:
Ensure you're up-to-date with immunizations before your trip. Be cautious of street food and only drink bottled or filtered water.
To protect your belongings, it's recommended to use a money belt or lockable bag.

Local Etiquette and Respect:
Vietnamese people are generally friendly and respectful. Ensure you reciprocate this respect by dressing modestly, especially in religious sites. It is customary to remove your shoes before entering local homes and certain temples. Offering a polite 'xin chào' (hello in Vietnamese) can also be appreciated.