Hello! I heard you're planning a trip to Pesé, Chitré, and Las Tablas, in Panama. That sounds like an exciting adventure! Here are some travel tips for your journey.

Best Time to Visit:
The best time to visit these places would be during their dry season, which is from mid-December to mid-April. This is when you'll experience less rainfall and more sun. However, if you're interested in experiencing local festivities, visiting in January-March might be ideal for the worldwide famous 'Carnaval' celebrations, especially in Las Tablas.

Route and Accessibility:
To reach Pesé, Chitré, and Las Tablas, you can fly into the Tocumen International Airport in Panama City. From there, you can take a bus ride, hire a cab or rent a car to reach these destinations. Public transportation in Panama is reliable making these towns easily accessible.

Accommodation and Booking:
You will find a range of accommodations in these towns, from budget-friendly homestays and local guesthouses, to more luxurious hotels. It's always safer to book your accommodation in advance through reliable online platforms like Booking.com and Airbnb, especially during peak season.

Clothing and Essentials:
Light clothing is ideal due to the tropical climate. Rain gear is a must if you are traveling in the wet season. Also, don't forget sunscreen, bug spray, a hat, and a reusable water bottle to stay hydrated.

Health and Safety:
No specific vaccinations are required for Panama, but it's always best to be up-to-date on routine vaccines. Basic health facilities are available in these towns. Drinking tap water is not recommended, so stick to bottled water. Make sure you have travel insurance for any emergencies.

Local Etiquette and Respect:
Panamanians are generally very polite and somewhat formal. Spanish is their primary language, so learning a few basic words would help you. Tipping is customary in Panama. Also, the country is religious, so dressing modestly when visiting religious sites is highly appreciated.