Certainly! I can give you several tips that should make your trip to Casablanca, Marrakech, Fes, and Meknes more enjoyable.

Best Time to Visit:
April through June and September through November are ideal times to visit these cities due to the moderate weather. Avoid the peak of summer as the heat can be intense.

Route and Accessibility:
Inter-city trains, buses, and taxis are reliable and convenient ways to travel between these cities. Casablanca and Marrakech also have international airports for ease of access.

Altitude and Acclimatization:
These cities are not at high altitudes so you should not need time to acclimatize. However, be aware of the heat especially in the summer months.

Accommodation and Booking:
There are several options ranging from luxury hotels to more affordable guest houses and Riads (traditional Moroccan houses), so it's advisable to book in advance especially during the tourist seasons.

Clothing and Essentials:
Pack light, loose clothing to combat the heat. An exception would be during the winter when temperatures can drop quite low, especially at night. Always bring a good pair of walking shoes and don’t forget your sunscreen, a hat, and sunglasses.

Health and Safety:
Stay hydrated and protect yourself from the sun. Be cautious of street food, and only eat at well recommended establishments to avoid any potential stomach upsets. Hospitals in major cities are generally of good quality. Always keep an eye on your belongings in crowded areas to avoid pickpockets.

Local Etiquette and Respect:
Locals appreciate if tourists make an effort to respect their customs. Modest clothing is recommended, particularly for women. Remember that Morocco is a Muslim country, so respect local traditions, particularly during the holy month of Ramadan. Also, haggling in markets is part of the culture, so don't shy away from bargaining hard for what you want.