Hello! Sounds like an exciting trip to France is coming up! I'd be happy to provide some travel tips for your visit to Dijon, Beaune, and Lyon.

Best Time to Visit:
The best time to visit these regions in France is late spring (April to June) or early fall (September to October). The weather is typically mild with lesser crowds during these periods.

Route and Accessibility:
Upon arrival at Charles De Gaulle (or Orly) Airport, Paris, you can take a train from Gare de Lyon to all these destinations. All are also accessible by car or bus from Paris. Intra-city travel can be easy using public transport or by renting a bicycle which is popular in these regions.

Accommodation and Booking:
There's a wide range of hotels and guesthouses available in these cities. To get the best options, make sure to book in advance – especially in the peak season. Websites like Booking.com, Airbnb, or local French booking sites might offer good deals.

Clothing and Essentials:
Light clothing is suitable for the days but nights can get chilly, so a light jacket or sweater is recommended. Don't forget to carry a good pair of walking shoes, as exploring these historical cities often involves walking around. Umbrella or raincoat may come in handy as scattered rain showers are common, especially during spring and fall.

Health and Safety:
France is generally safe, but it's always important to stay aware of your surroundings. European Health Insurance Card holders can access health care services in France. Non-EU citizens should ensure they have suitable travel insurance.

Local Etiquette and Respect:
French people appreciate politeness. A simple 'Bonjour' (Hello), 'Merci' (Thank you), or 'Excusez-moi' (Excuse me) can go a long way. Try to adapt to local customs such as greeting with a kiss on the cheek. Respecting historical sites and being courteous to locals is always a good practice.