Absolutely, visiting the Venezuelan cities of Caracas, Valencia, and Maracaibo can be an exciting experience. Here are some travel tips for your journey:

Best Time to Visit:
The most suitable time to visit these cities is during their dry season which is from December to April. The relatively cooler temperature and lesser rainfall during these months provide more enjoyable tour conditions.

Route and Accessibility:
With Caracas being the capital city, most international visitors enter Venezuela via Simón Bolívar International Airport in Caracas. Domestic travel is quite efficient via air travel or by road, though the quality of roads can vary greatly.

Altitude and Acclimatization:
While Caracas is near sea level, it is also surrounded by the Avila mountain range - particularly if you venture to El Avila National Park, be aware of the altitude change. Adjust your activities accordingly to get acclimatized.

Accommodation and Booking:
A wide range of accommodation options are available, from luxury hotels to more affordable lodgings. Airbnb is also a great option. Remember to book in advance, particularly during the peak travel season.

Clothing and Essentials:
Weather can be variable due to geographical variants, so layering your clothes is a good idea. Always carry essentials like sunscreen, hat, and sunglasses to protect against the sun. Mosquito repellent is also recommended.

Health and Safety:
Venezuela has been facing political and economic difficulties, so it's crucial to stay informed about the current situation. Check travel advisories regularly, and be cautious about your safety, particularly in large cities.

Local Etiquette and Respect:
The Venezuelan people are warm and friendly, but it's important to respect local culture and customs. Learn a few basic phrases in Spanish, as it's the national language and will make your interaction with locals easier and more enjoyable.