Sure! Here are some travel tips for your trip to Toronto and Muskoka:

Best Time to Visit:
The best time to visit Toronto and Muskoka is from late April through June and September through October. These periods offer pleasant weather and fewer tourists.

Route and Accessibility:
Toronto is easily accessible by air through Toronto Pearson International Airport. From Toronto, you can reach Muskoka either by car or bus. It is about a 2 hours drive. Ontario Northland also operates bus services from Toronto to Muskoka.

Altitude and Acclimatization:
Both Toronto and Muskoka are at low altitudes and acclimatization is generally not an issue.

Accommodation and Booking:
You can find a variety of accommodation options in both Toronto and Muskoka ranging from budget hotels to luxury resorts. Always book in advance to get the best rates and available options.

Clothing and Essentials:
Depending on the season of your travel, pack accordingly. If you're travelling in Spring or Fall, carry a jacket as temperatures can fluctuate. Summers are typically warm, so pack light clothing but remember to take hats, sunglasses, and sunscreen. For winters, pack heavy winter clothing.

Health and Safety:
Both Toronto and Muskoka are safe for tourists. Just follow regular safety precautions like not leaving your belongings unattended and avoiding lonely places at night.

Local Etiquette and Respect:
Canadians are generally polite and respectful. Just maintain normal courtesy like waiting your turn, saying please and thank you, and respecting the personal space of others.

Activities:
Try to visit the CN Tower in Toronto and don't miss out on boat tours in Muskoka. Toronto's unique neighborhoods like Chinatown, Little Italy, Kensington Market etc are also worth exploring. In Muskoka, make sure to explore nature trails and enjoy water sports.