Hi there! It's fantastic to hear that you are planning a trip to Manaus, Santarém, and Belém. Here are some tips to help you prepare:

Best Time to Visit:
The best time to visit Manaus and the nearby areas is typically during the dry season, which runs from June to September. However, be aware that the weather can still be quite hot, with July usually being the warmest month. Santarém and Belém also have similar climatic conditions.

Route and Accessibility:
You can reach Manaus via the Eduardo Gomes International Airport. There are boat services from Manaus to Santarém, but it's a long ride, usually taking a couple of days. Alternatively, you can take a flight to Santarém. To reach Belém from Santarém, you can either choose a ferry ride through the Amazon river or an easy flight.

Accommodation and Booking:
There's plenty of hotels and lodges to suit a range of budgets in all these cities. Online travel platforms such as Booking.com, Expedia or Airbnb can be used to compare prices and book in advance.

Clothing and Essentials:
Pack light clothes that breath well due to the hot and humid weather. A good insect repellent, sun block and a hat would also come in handy. Don't forget rain gear, as sudden showers are common, even in the dry season.

Health and Safety:
Make sure you are up-to-date on routine vaccines before your trip. You might want to consider vaccines for diseases like Yellow Fever that are prevalent in the region. Always drink bottled water, and be cautious while swimming or doing water activities due to the presence of certain parasites in the fresh water bodies.

Local Etiquette and Respect:
Be respectful to the local traditions and norms. Avoid littering, especially while exploring the Amazon rainforest. When interacting with indigenous communities, take guidance from a knowledgeable tour guide to avoid unintentionally offensive behaviors.