Absolutely! Tulcea, Sulina, and Sfântu Gheorghe are beautiful destinations in Romania, each with its unique characteristics. Here are some travel tips to assist you:

Best Time to Visit:
These places are widely famous for their natural beauty and wildlife. Hence, the best time to visit is May to September when the weather is agreeably warm, and the wildlife like birds or dolphins are active.

Route and Accessibility:
All three towns are part of the Danube Delta, and the best way to get there is via Tulcea, which is connected by road to major Romanian cities. From Tulcea, you can take a boat to Sulina or Sfântu Gheorghe.

Altitude and Acclimatization:
The elevation of these areas are not high, it is very close to the sea level. Therefore, altitude sickness is not a concern in these areas. Acclimatization is generally not required.

Accommodation and Booking:
Accommodation options are quite limited in these areas due to its rural locality, making pre-booking essential. Both Sulina and Sfântu Gheorghe offer guesthouses and homestay options.

Clothing and Essentials:
Given that you'll likely be exploring nature and wildlife, comfortable footwear are a must. During the summer, wear light clothing but carry a jacket for the cooler evenings. Bring a raincoat or umbrella, even in the summer, as rains can be unpredictable.

Health and Safety:
Carrying a basic first aid kit and insect repellent can be beneficial. Also, if you're planning a boat trip in the Danube Delta, sunscreen, sunglasses, and a wide-brimmed hat are essential to protect yourself from the sun.

Local Etiquette and Respect:
As in any destination, show respect for local customs and traditions. In Romania, a simple greeting in the local language such as "buna ziua" (good day) can go a long way in building connections with locals.