Hello! That sounds like an exciting trip. Here are some travel tips for your visit to Bayreuth, Weimar, Leipzig, and Dresden in Germany.

Best Time to Visit:
The best time to visit these cities in Germany is generally between May and September when you can enjoy warm weather and outdoor events. However, December is also a popular time for Christmas markets.

Route and Accessibility:
All four cities are well connected by Germany's extensive railway system. Bayreuth is in northern Bavaria; Weimar, Leipzig, and Dresden are in the eastern part of the country. You can easily reach these cities by trains from major German cities like Munich, Berlin, or Frankfurt.

Accommodation and Booking:
Germany offers a variety of accommodations to suit all budgets. It's advisable to book your accommodations in advance. A range of options from luxury hotels to cost-effective hostels are available in all these cities. Many people use online booking platforms like Booking.com, Airbnb, or the local German platform HRS.

Clothing and Essentials:
The clothing you should pack entirely depends on the season. Summers can be quite warm, so be sure to bring light, breathable clothing. However, winters can be very cold, especially in eastern Germany, so warm clothing is essential. Comfortable footwear is advised as these cities are rich in historic sites that might require considerable walking.

Health and Safety:
Germany is generally safe, but it's always wise to take common travel precautions. Always keep an eye on your belongings, especially in crowded places. Germany has a robust healthcare system, and pharmacies are easily accessible. However, it's recommended to have travel insurance that covers health.

Local Etiquette and Respect:
The Germans value punctuality, so it's essential to be on time. Tipping is customary in restaurants and cafés, and the norm is to tip about 5-10% of the bill. When visiting any religious site, ensure to respect the dress code and the ongoing religious services.