Of course! A trip to Istanbul, Bursa, and Edirne is sure to be a trip filled with amazing history, food, and culture. Here are some travel tips for your adventure:

Best Time to Visit:
The best time to visit these Turkish cities is during the spring (April to June) and fall (September to November) when the weather is moderate. Summers can be very hot and winters can be quite cold.

Route and Accessibility:
Istanbul is a major international hub, so it's easily accessible from anywhere in the world. From Istanbul, Bursa is about a 2 hours drive to the south, and from Bursa, Edirne is about a 3.5-hour drive to the northwest.

Altitude and Acclimatization:
These cities don't sit at a significant altitude, so there's no need to worry about acclimatization.

Accommodation and Booking:
These cities have a wide range of accommodations that suit all budgets, from luxury hotels to hostels. It’s advisable to book in advance if you’re visiting during the peak season.

Clothing and Essentials:
Even though Turkey is a fairly liberal country, it's good to dress modestly, especially when visiting religious sites. Don’t forget to pack a good pair of walking shoes and a scarf for women to cover their heads when visiting mosques.

Health and Safety:
Turkish cities are relatively safe. However, ensure you have travel insurance. Also, always keep an eye on your personal belongings, especially in crowded areas and during travel on public transport.

Local Etiquette and Respect:
The Turkish people are known for their fantastic hospitality. A respectful attitude towards local customs and traditions will be appreciated. It's also worth learning a few basic Turkish phrases.