Hello! That's a great choice of destinations. Here are some tips for your travels to Cusco, Arequipa, and Ica, in Peru.

Best Time to Visit:
The best time to visit these cities in Peru is during the dry season, between May and September. The weather is pleasant and it’s the perfect time to explore the ancient Inca ruins or the mesmerizing countryside.

Route and Accessibility:
You can reach Cusco, your first destination, by flight, arriving at Alejandro Velasco Astete International Airport. From Cusco, there's a bus or a car ride to Arequipa. For Ica, you can take a bus or a flight back to Lima and then go on to Ica by bus.

Accommodation and Booking:
All three cities offer a wide range of accommodations from luxury hotels to budget hostels. It's best to book in advance, especially during the tourist season. Websites like Booking.com, Airbnb can be used for bookings.

Clothing and Essentials:
Pack lightly but include layers for the warm days and cold nights. A rain jacket, comfortable walking shoes, sunscreen, hat, sunglasses, and a sturdy water bottle are must-haves. You should also carry some cash, as not all places accept credit cards.

Health and Safety:
Not all tap water is safe to drink in Peru, so drink bottled or treated water. Don't forget to take travel insurance, and pack a first aid kit with required medicines. Peru is generally safe but stay cautious of your belongings in crowded areas.

Local Etiquette and Respect:
Be respectful of the local culture and traditions. When visiting religious sites or rural areas, dressing modestly is recommended. Try to learn few basic phrases in Spanish, it will be greatly appreciated by the locals.