Sure! A trip to France taking in Paris, Bordeaux, and Nice offers a delightful blend of urban charm, wine country and the Riviera. Here are some tips to make your journey more enjoyable:

Best Time to Visit:
The best time to visit France is during the spring (April to June) or fall (September to November) when there are fewer tourists, mild weather, and lower prices. The summer can get quite warm, and Paris and Nice attract lots of tourists.

Route and Accessibility:
The cities are well connected by France's efficient train system. From Paris, you can take a direct train to Bordeaux; the journey takes around 2 hours. From Bordeaux to Nice, the train ride is longer, around 6 hours. Hiring a car could be an alternative to see the countryside up-close, but be prepared for toll fees on French highways.

Altitude and Acclimatization:
These places are at relatively low altitude so you shouldn't face any issues related to acclimatization.

Accommodation and Booking:
France offers a wide range of accommodation options - from luxury hotels to budget hostels. It is advisable to book in advance, especially during peak tourist season.

Clothing and Essentials:
Pack clothing suitable for the season of your visit. Summer can be hot, spring and autumn mild; winters, especially in Paris, may require a good coat, a scarf, and gloves. Comfortable walking shoes are a must, as these cities are best explored on foot. Don't forget your charger adaptor, sunscreen and a good quality camera.

Health and Safety:
France is generally safe but it's advisable to have travel insurance for sudden health issues or thefts. Always be aware of your surroundings and beware of pickpockets in touristy areas.

Local Etiquette and Respect:
French people appreciate it when you greet them in French, so learning a few basic phrases can be helpful. Remember to say 'Bonjour' (Good day) or 'Bonsoir' (Good evening), followed by 'Monsieur' or 'Madame', depending on the time of day and whom you're addressing. In restaurants, a service charge is typically included in your final bill but leaving a few more euros is a good gesture.