Sure, here are the travel tips for your visit:

Best Time to Visit:
The best time to visit Uruguay, including Montevideo, Paysandú and Punta Del Este, is during their summer months, from December to March when the weather is warm and sunny.

Route and Accessibility:
You will likely fly into Montevideo's Carrasco International Airport, the main international gateway to Uruguay. From there, you can take buses or taxis to get to Paysandú and Punta Del Este.

Altitude and Acclimatization:
The highest point in Uruguay is just 514 meters, so no acclimatization is needed for your trip.

Accommodation and Booking:
Book your accommodations in advance in all three cities, especially during the peak summer months.

Clothing and Essentials:
Bring lightweight clothing for the summer months, but do pack a light sweater or sweatshirt for cool evenings. Remember to pack a swimsuit so you can enjoy the beautiful beaches in Punta Del Este.

Health and Safety:
No particular vaccines are required for Uruguay. Tap water is safe to drink. Carry a basic first aid kit and any personal medications. Make sure to keep yourself hydrated and apply sunscreen regularly.

Local Etiquette and Respect:
Uruguayans are known for their friendly and warm hospitality. Respect local customs and traditions. When visiting religious or official buildings, dressing modestly is suggested. Spanish is the national language, so learning a few basic phrases can be helpful and appreciated.