Hello! It's great to hear that you're planning a trip to Prague, Brno, and Ostrava. Here are some travel tips for your journey.

Best Time to Visit:
The best time to visit these cities in Czech Republic is during the spring (April to June) and fall (September to October) when the weather is pleasant and the tourist crowds are smaller.

Route and Accessibility:
You can easily access Prague, Brno, and Ostrava via direct flights from major cities worldwide. From Prague, it's convenient to travel to Brno and Ostrava by train or car over the Czech Republic's well-connected road and rail networks.

Accommodation and Booking:
Each city offers a wide range of accommodations, from luxury hotels to budget hostels. It's recommended to book your accommodation in advance, especially during the peak tourist seasons, using online portals like Booking.com or Airbnb for the best deals.

Clothing and Essentials:
Pack layers as the weather can change quickly. Don’t forget your comfortable walking shoes as these cities are best explored on foot. An umbrella or rain jacket might come in handy for unexpected showers. Also, pack a good quality camera to capture the beautiful architecture and landscapes.

Health and Safety:
Czech Republic is generally safe. However, be cautious of your belongings in crowded areas and keep emergency contact numbers handy just in case. It's worth getting comprehensive travel insurance which covers health.

Local Etiquette and Respect:
Czechs appreciate politeness and a level of formality. A handshake is common while meeting someone for the first time. Tipping in restaurants is customary and is usually around 10-15% of the bill. Also, it's considered respectful to stay quiet in public transport and public places.