Absolutely! That sounds like a fantastic trip. Here are some travel tips that may help:

Best Time to Visit:
The best time to visit these places in southwestern United States is from March to May and September to November, when temperatures are moderate.

Route and Accessibility:
I would recommend starting in Albuquerque, go north to Santa Fe, then continue north to Taos, New Mexico. From Taos, head northwest to Durango, Colorado. Each location is accessible by car and public transportation.

Altitude and Acclimatization:
Albuquerque is about 5,312 feet, Santa Fe is 7,260 feet, Taos is about 6,969 feet and Durango is at 6,512 feet above sea level. To avoid altitude sickness, hydrate regularly, avoid intense physical exertion and imbibe alcoholic drinks only in moderation if at all.

Accommodation and Booking:
There are several hotels and vacation rentals in all of these places. I would recommend booking your accommodations in advance, especially if you are visiting during peak tourism season.

Clothing and Essentials:
Prepare for a variety of temperatures as night temperatures can drop significantly. Rememeber to pack some comfortable walking shoes, a hat, sunscreen, and sunglasses.

Health and Safety:
Always stick to marked trails if you're hiking and carry a map. Water refill stations might not be available everywhere, so pack enough.

Local Etiquette and Respect:
The southwest area of the United States is rich in Native American history and culture, be sure to respect the local customs and traditions. Note that some areas may have photographs restrictions, especially in Native American reservations.