Absolutely! Penonomé, Ocú, and Las Tablas are all wonderful destinations in Panama. Here are some tips for your travel:

Best Time to Visit:
The dry season (mid-December to mid-Aprilenomé, ) is the best time to visit these places. During this time, the weather is warm and there's little rain.

Route and Accessibility:
Penonomé is the capital of Coclé province, located along the Inter-American Highway. To reach Ocú and Las Tablas, you'd have to head west from Penonomé, passing through Natá and continuing onwards. Regular bus services are available from Penonomé to both Ocú and Las Tablas.

Altitude and Acclimatization:
These areas are located at low altitudes, so travelers typically won't need time to acclimatize. However, it's still important to stay hydrated, especially in the heat of the day.

Accommodation and Booking:
Both Las Tablas and Penonomé have a variety of hotels and hostels. It's recommended to book your accommodations in advance, particularly if you're traveling during the busy season.

Clothing and Essentials:
Lightweight, breathable clothing is best for the tropical climate. Don't forget to pack a hat, sunblock, and insect repellent.

Health and Safety:
Ensure that your routine vaccinations are up to date. Carry a basic first-aid kit and any prescribed medications you may need. Always remember to take care of your personal belongings.

Local Etiquette and Respect:
Panamanians are welcoming and appreciative of visitors who take the trouble to learn a few phrases in Spanish. In local tradition, it's also considered polite to greet shop owners when entering their businesses. Respect local customs and traditions especially during public festivals and events.

Don't forget to explore the local cuisine, culture, and enjoy your visit! Happy Travelling!