Sure! Here're some travel tips for your journey across Russia:

Best Time to Visit:
For tourist sites in Moscow, late spring-early June is a good time to visit when the city is beautifully green. For Siberian cities like Yekaterinburg, Novosibirsk, Irkutsk, and Vladivostok, the summer months of July and August would be better, though colder months offer a unique winter wonderland experience especially around Lake Baikal (Irkutsk).

Route and Accessibility:
You could consider taking the Trans-Siberian railway from Moscow to Vladivostok, it stops at all these cities. It's the world's longest railway line, providing a unique experience over about a week of travel.

Altitude and Acclimatization:
Most places lie at low altitudes, so you don't need to worry about high-altitude sickness. But do allow some time to adjust to the cold weather, especially in Siberia.

Accommodation and Booking:
Accommodations vary from city to city. Moscow and Vladivostok have a range of hotels, but accommodation can be basic in smaller cities. It's advisable to book accommodation and any desired tours in advance.

Clothing and Essentials:
Pack for cold weather, especially if you're traveling in winter (down jacket, thermal layers, gloves, hat, sturdy winter boots). In summer, layering works best as temperatures can vary. Also pack essentials like a first-aid kit and personal medications.

Health and Safety:
Have travel insurance that includes medical coverage. Stick to well-lit, populated places at night and keep an eye on your belongings in crowded places to avoid pickpocketing.

Local Etiquette and Respect:
Learn a few basic Russian phrases, it will go a long way with locals. Dress conservatively when visiting orthodox Cathedrals (Knees and shoulders should be covered). Always ask for permission before taking photos of people, and avoid discussing political topics.