Absolutely, Mendoza, San Juan, and La Rioja are regions in Argentina renowned for their beautiful landscapes and spectacular wine. Here are some travel tips for your journey:

Best Time to Visit:
The best time to visit these wine regions is during the harvest season, which is typically from late February to early April. The weather during this time is pleasant, and you can witness the wine-making process up close.

Route and Accessibility:
All three locations are accessible by road and air, with Mendoza also having an international airport. If you are driving, make sure you are comfortable with long drives as there can be significant distances between cities and attractions.

Altitude and Acclimatization:
While all three cities are not at extreme altitudes, remember to take it easy in the first couple of days to adjust to the change in altitude. Stay hydrated and make sure to get enough rest.

Accommodation and Booking:
There is a variety of accommodations ranging from budget to luxury in all three regions. It's recommended to make bookings well in advance, especially during harvest season when accommodations can be limited.

Clothing and Essentials:
Carry comfortable clothing suitable for warm daytime and cooler nights. Don't forget to bring a hat and sunblock to protect yourself from the sun. Comfortable shoes are always suggested as you may be walking extensively at vineyards.

Health and Safety:
Ensure travel insurance covers any health concerns. Stay hydrated, carry a first aid kit and personal medication if necessary. In remote areas, medical facilities can be limited.

Local Etiquette and Respect:
Argentina is a country rich in traditions and customs. While you're there, respect local customs and traditions especially when you are visiting rural vineyards. Consider learning some polite Spanish phrases, as English may not be widely spoken in these regions. When tasting wine, it's customary to not drink the entire glass after each pour. Enjoy your travel!